Isopropylamine (monoisopropyl amine, MIPA, 2-Propylamine) is an organic compound, an amine. It is a hygroscopic colorless liquid with ammonia-like odor. It is miscible with water and flammable. It is a valuable intermediate in chemical industry. Isopropylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point -35°F. Boiling point 90°F. Less dense than water Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a solvent and to make other chemicals.
Suggested titleIsopropylamine

Primary amines

Molar mass59 g/mol
Gross formula3 H 9 N


Obtaining amines from alcohols

Obtaining amines from alcohols

propanol-2 + ammonia → (t°, cat) → isopropylamine + water

The reaction can continue until secondary and tertiary amines are obtained, in practice a mixture of products is obtained.

Displacement of amines from their salts by stronger bases

Propanamine-2 amine displacement

isopropylammonium iodide + sodium hydroxide → isopropylamine + sodium iodide + water

Hydrogenation of nitro compounds*

Propanamine-2 hydrogenation

2-nitropropane + 3 hydrogen → (t°, nickel) → isopropylamine + 2 water

Recovery in an alkaline or neutral environment*

Propanamine-2 Zinin reaction, recovery

2-nitropropane + 3 ammonium sulfide → isopropylamine + 3 sulfur + 6 ammonia + 2 water

Decomposition of unstable carboxylic acids*

Propanamine-2 decomposition

2-methylalanine → (t°) → isopropylamine + carbon dioxide

Chemical properties

The main properties of amines, obtaining ammonium compounds

Propanamine-2 neutralization with acids

isopropylamine + hydrochloric acid → isopropylammonium chloride

N-alkylation of amines, obtaining secondary and tertiary amines

Propanamine-2 N-alkylation

Isopropylamine + chloroethane + sodium hydroxide → isopropylethylamine + sodium chloride + water

The reaction is carried out in two stages. The intermediate product is a salt, which can be treated with alkali to isolate the amine.
Above is the summary equation of the two reactions.

Preparation of ammonium compounds with halogen derivatives

Propanamine-2 received. ammonium compound

isopropylamine + chloroethane → isopropylethylammonium chloride

Reaction of primary amines with nitrous acid*

Propanamine-2 reaction with nitrous acid

isopropylamine + sodium nitrite + hydrochloric acid → propanol-2 + nitrogen↑ + sodium chloride + water

This is a qualitative reaction to primary amines, sign: gas evolution N2 . The reaction proceeds in two stages: sodium nitrite with hydrochloric acid give nitrous acid, which reacts with the amine. To get a simplified record of the reaction, press the ≡ button.


Propanamine-2 burning

4 isopropylamine + 21 oxygen → (t°) → 12 carbon dioxide + 18 water + 2 nitrogen


Alexander Stephenson

Candidate of Chemical Sciences, editor-in-chief of Lecturer at several international online schools, member of the jury of chemistry competitions and author of scientific articles.

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